• 36 gauge (110 micron) injection needles available
• potential applications:
• brain injection
• intrauterine mouse embryo injection
• retinal pigment epithelium injection
• intraocular injection
• low dead volume allows oil-free injection

Change tips during experiments
When the inner diameter of the tip on a conventional syringe is reduced to less
than 100 micron, it is very difficult to back fill the solution at a reasonable speed.
NanoFil solves this problem by using a tip coupling mechanism that makes it
possible to change the syringe tip during the experiment. Simply load the sample
using a larger tip, such as the 26 gauge needle provided with the syringe,
and then replace it with a micro tip for sample injection. On a conventional
10 microliter syringe, a solid ring or bushing is permanently bonded to the
tubing. Replacing the tip in middle of the experiment is not practical. With the
NanoFil, different gauge tips can be exchanged on the syringe by a simple twist
of the brass lock, gently pulling out the tip, and replacing with the desired new
tip. The silicone gasket makes it possible to hold not only metal tips but also
glass and quartz tubing. Many types of tubing can be easily connected to the
syringe as long as the outer diameter (OD) is close to, but not more than, the
inner diameter (ID) of the inside barrel. The application potential of this design
is tremendous. Flexible quartz capillaries used in Gas Chromotography (GC) and
Capillary Electrophoresis (CE) can also be easily coupled to the syringe.
Specially designed tips as small as 36 gauge (110 micron OD) are offered in
both blunt and beveled styles. Our studies have shown that these tips will cause
less trauma to the tissue than any other form of micro syringe currently in use.
NanoFil has a unique coupling mechanism that allows many different forms of
small tubing and tips to be coupled with the syringe barrel.